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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,223 Asian ancestry cases, 96,119 Asian ancestry controls, 20 African ancestry cases, 1,406 African ancestry controls, 14 Hispanic or Latin American cases, 2,457 Hispanic or Latin American controls, 1,389 European ancestry cases, 351,259 European ancestry controls; replicated in 410 African ancestry cases, 7,385 African ancestry controls, 48 Hispanic or Latin American cases, 615 Hispanic or Latin American controls, 2,456 European ancestry cases, 243,876 European ancestry controls.
The effect
The reported allele is T; the catalogue records no effect size
; p = 2 × 10−12.
Where it sits Chromosome 13, band 13q12.3 — between genes, 34.7 kb from EIF4A1P7.
What each result means
C/CNo copy of the version the research linked to Preeclampsia or eclampsia. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Preeclampsia or eclampsia. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Preeclampsia or eclampsia. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs7318880 is a single position in the genome, in or near the near EIF4A1P7 gene. Published research associates it with preeclampsia or eclampsia. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7318880 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7318880 come from?
GWAS Catalog, Nature medicine 2023, PMID:37248299. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Preeclampsia or eclampsia (rs7318880). MyGeneLog™. https://www.mygenelog.com/variants/rs7318880