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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 6,879 Icelandic ancestry individuals.
The effect
Each copy of the A allele shifted the measure 0.49 SD units lower (95% confidence interval 0.34-0.63); p = 1 × 10−11.
Where it sits Chromosome 12, band 12q13.12 — inside PRPH.
What each result means
A/ATwo copies of the version the research linked to Sural nerve amplitude potential. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Sural nerve amplitude potential. That is a smaller link than two copies.
G/GNo copy of the version the research linked to Sural nerve amplitude potential. This is the starting point the study compared everyone against.
Nature communications · 2019 · PMID 30992453 · open access
Questions about rs73112142
What is rs73112142?
rs73112142 is a single position in the genome, in or near the PRPH gene. Published research associates it with sural nerve amplitude potential. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs73112142 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73112142 come from?
GWAS Catalog, Nature communications 2019, PMID:30992453. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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