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Mean platelet volume

RP4-576H24.2 · rs73076965

Where this position leads

Condition: Blood Cell Counts

rs73076965 Condition: Blood Cell Counts Blood Cell Counts Condition rs73076965 rs73076965 RP4-576H24.2

What the study found

Who was studied 164,454 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0542 lower (95% confidence interval 0.045-0.063); p = 6 × 10−33.

How common The G allele had a frequency of about 20% in the people studied.

Where it sits Chromosome 20, band 20p13 — in an intron of SIRPD.

What each result means

A/A No copy of the version the research linked to Mean platelet volume. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Mean platelet volume. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Mean platelet volume. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73076965

What is rs73076965?

rs73076965 is a single position in the genome, in or near the RP4-576H24.2 gene. Published research associates it with mean platelet volume. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73076965 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs73076965 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73076965 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Mean platelet volume (rs73076965). MyGeneLog™. https://www.mygenelog.com/variants/rs73076965

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