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Face memory

KIF15 · rs73076581

Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.

What the study found

Who was studied 523 European ancestry schizophrenia cases, 100 Latino schizophrenia cases, 827 European ancestry controls, 83 Latino controls.

The effect Each copy of the T allele shifted the measure 0.722 lower (95% confidence interval 0.45-1); p = 4 × 10⁻⁸.

Where it sits Chromosome 3, band 3p21.31 — in an intron of KIF15.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Face memory — no copies of the reported risk allele.

A/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Face memory.

T/T Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Face memory compared to the general population.

Source

Genome-wide Association of Endophenotypes for Schizophrenia From the Consortium on the Genetics of Schizophrenia (COGS) Study

Greenwood TA, Lazzeroni LC, Maihofer AX, Swerdlow NR, Calkins ME, Freedman R, Green MF, Light GA, Nievergelt CM, Nuechterlein KH, Radant AD, Siever LJ

and 9 more — show all

Silverman JM, Stone WS, Sugar CA, Tsuang DW, Tsuang MT, Turetsky BI, Gur RC, Gur RE, Braff DL

JAMA psychiatry · 2019 · PMID 31596458

Questions about rs73076581

What is rs73076581?

rs73076581 is a single position in the genome, in or near the KIF15 gene. Published research associates it with face memory. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73076581 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73076581 come from?

GWAS Catalog, JAMA Psychiatry 2019, PMID:31596458. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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