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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 430 Han Chinese ancestry cases, 482 Han Chinese ancestry controls; replicated in 800 Han Chinese ancestry cases, 900 Han Chinese ancestry controls.
The effect
Each copy of the G allele carried 1.63 times the odds of Chronic spontaneous urticaria (95% confidence interval 1.4-1.9); p = 3 × 10−10.
How common The G allele had a frequency of about 13% in the people studied.
Where it sits Chromosome 3, band 3p21.31 — between genes, 1.1 kb from LRRC2.
What each result means
A/ANo copy of the version the research linked to Chronic spontaneous urticaria. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Chronic spontaneous urticaria. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Chronic spontaneous urticaria. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2023 · PMID 35933036
Questions about rs73075571
What is rs73075571?
rs73075571 is a single position in the genome, in or near the near LRRC2 gene. Published research associates it with chronic spontaneous urticaria. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs73075571 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73075571 come from?
GWAS Catalog, The Journal of investigative dermatology 2023, PMID:35933036. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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