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Male-pattern baldness

TWIST1 · rs73071393

Where this position leads

Condition: Androgenetic Alopecia (Male Pattern Baldness)

rs73071393 Condition: Androgenetic Alopecia (Male Pattern Baldness) Androgenetic Alopecia (Male Pattern… Condition rs73071393 rs73071393 TWIST1

What the study found

Who was studied 52,874 British ancestry males.

The effect Each copy of the G allele shifted the measure 0.0809 lower; p = 5 × 10−8.

Where it sits Chromosome 7, band 7p21.1 — inside TWIST1.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Male-pattern baldness — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Male-pattern baldness.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Male-pattern baldness compared to the general population.
Source

Questions about rs73071393

What is rs73071393?

rs73071393 is a single position in the genome, in or near the TWIST1 gene. Published research associates it with male-pattern baldness. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73071393 linked to?

On MyGeneLog this position is linked to Androgenetic Alopecia (Male Pattern Baldness). The research behind each link, and its sources, are set out on that condition page.

Does having rs73071393 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73071393 come from?

GWAS Catalog, PLoS Genet 2017, PMID:28196072. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Male-pattern baldness (rs73071393). MyGeneLog™. https://www.mygenelog.com/variants/rs73071393

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