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Body fat distribution (arm fat ratio)

near RPL35AP28 · rs7306275

What the study found

Who was studied 55,006 British ancestry males, 61,132 British ancestry females; replicated in 112,425 British ancestry males, 133,936 British ancestry females.

The effect The reported allele is A; the catalogue records no effect size ; p = 1 × 10−14.

How common The A allele had a frequency of about 36% in the people studied.

Where it sits Chromosome 12, band 12q13.12 — between genes, 6.8 kb from RPL35AP28.

What each result means

A/A Two copies of the version the research linked to Body fat distribution (arm fat ratio). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Body fat distribution (arm fat ratio). That is a smaller link than two copies.
G/G No copy of the version the research linked to Body fat distribution (arm fat ratio). This is the starting point the study compared everyone against.
Source

Questions about rs7306275

What is rs7306275?

rs7306275 is a single position in the genome, in or near the near RPL35AP28 gene. Published research associates it with body fat distribution (arm fat ratio). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7306275 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7306275 come from?

GWAS Catalog, Nature communications 2019, PMID:30664634. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Body fat distribution (arm fat ratio) (rs7306275). MyGeneLog™. https://www.mygenelog.com/variants/rs7306275

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