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COVID-19

SLC6A20 · rs73062389

What the study found

Who was studied 11,778 European ancestry cases, 357,198 European ancestry controls.

The effect Each copy of the A allele carried 1.25 times the odds of COVID-19 (95% confidence interval 1.19-1.31); p = 4 × 10−19.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 3, band 3p21.31 — in an intron of SLC6A20.

What each result means

A/A Two copies of the version the research linked to COVID-19. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to COVID-19. That is a smaller link than two copies.
G/G No copy of the version the research linked to COVID-19. This is the starting point the study compared everyone against.
Source

Questions about rs73062389

What is rs73062389?

rs73062389 is a single position in the genome, in or near the SLC6A20 gene. Published research associates it with covid-19. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73062389 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73062389 come from?

GWAS Catalog, Frontiers in genetics 2021, PMID:35222515. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

COVID-19 (rs73062389). MyGeneLog™. https://www.mygenelog.com/variants/rs73062389

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