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Who was studied 120,246 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.0074 higher; p = 2 × 10−8.
How common The T allele had a frequency of about 16% in the people studied.
Where it sits Chromosome 19, band 19q13.33 — a synonymous change in PRR12.
What ClinVar records
ClassificationBenign for PRR12-related disorder; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2018-10-01.
ClinVar record 1297799NM_020719.3(PRR12):c.1830C>T (p.Ala610=)
What this is ClinVar's aggregate record for this position (as of its 2026-10-19 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CNo copy of the version the research linked to Fibrinogen levels. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Fibrinogen levels. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Fibrinogen levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
rs73058052 is a single position in the genome, in or near the PRR12 gene. Published research associates it with fibrinogen levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs73058052 linked to?
On MyGeneLog this position is linked to Fibrinogen and Blood Clotting. The research behind each link, and its sources, are set out on that condition page.
Does having rs73058052 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs73058052 come from?
GWAS Catalog, Hum Mol Genet 2015, PMID:26561523. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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