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Caffeine consumption from tea

PRR4 · rs73053413

What the study found

Who was studied 395,866 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0217 higher (95% confidence interval 0.016-0.028); p = 7 × 10−13.

How common The C allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 12, band 12p13.2 — between genes, 0.9 kb from SMIM10L1.

What each result means

C/C Two copies of the version the research linked to Caffeine consumption from tea. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to Caffeine consumption from tea. That is a smaller link than two copies.
T/T No copy of the version the research linked to Caffeine consumption from tea. This is the starting point the study compared everyone against.
Source

Questions about rs73053413

What is rs73053413?

rs73053413 is a single position in the genome, in or near the PRR4 gene. Published research associates it with caffeine consumption from tea. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73053413 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73053413 come from?

GWAS Catalog, Journal of the American Heart Association 2020, PMID:33287642. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Caffeine consumption from tea (rs73053413). MyGeneLog™. https://www.mygenelog.com/variants/rs73053413

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