Sensitive

Alzheimer's disease

ANKH · rs73048837

Where this position leads

Condition: Alzheimer's Disease

rs73048837 Condition: Alzheimer's Disease Alzheimer's Disease Condition rs73048837 rs73048837 ANKH

What the study found

Who was studied 56,184 European ancestry cases, 90,919 European ancestry controls.

The effect Each copy of the A allele carried 1.10 times the odds of Alzheimer's disease (95% confidence interval 1.07-1.14); p = 1 × 10−9.

How common The A allele had a frequency of about 7% in the people studied.

Where it sits Chromosome 5, band 5p15.2 — in an intron of ANKH.

What each result means

A/A Two copies of the version the research linked to Alzheimer's disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Alzheimer's disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Alzheimer's disease. This is the starting point the study compared everyone against.
Source

Questions about rs73048837

What is rs73048837?

rs73048837 is a single position in the genome, in or near the ANKH gene. Published research associates it with alzheimer's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73048837 linked to?

On MyGeneLog this position is linked to Alzheimer's Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs73048837 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73048837 come from?

GWAS Catalog, Nature genetics 2026, PMID:42237039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Alzheimer's disease (rs73048837). MyGeneLog™. https://www.mygenelog.com/variants/rs73048837

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