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Beta human chorionic gonadotropin in first trimester screening

near PSG9 · rs73037761

What the study found

Who was studied 52,791 Chinese ancestry individuals; replicated in 24,297 Chinese ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0918 higher (95% confidence interval 0.066-0.118); p = 8 × 10−12.

How common The A allele had a frequency of about 26% in the people studied.

What each result means

A/A Two copies of the version the research linked to Beta human chorionic gonadotropin in first trimester screening. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Beta human chorionic gonadotropin in first trimester screening. That is a smaller link than two copies.
G/G No copy of the version the research linked to Beta human chorionic gonadotropin in first trimester screening. This is the starting point the study compared everyone against.
Source

Questions about rs73037761

What is rs73037761?

rs73037761 is a single position in the genome, in or near the near PSG9 gene. Published research associates it with beta human chorionic gonadotropin in first trimester screening. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73037761 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73037761 come from?

GWAS Catalog, Nature genetics 2026, PMID:42509370. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Beta human chorionic gonadotropin in first trimester screening (rs73037761). MyGeneLog™. https://www.mygenelog.com/variants/rs73037761

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