Standard

Sum neutrophil eosinophil counts

MARK4 · rs73036517

Where this position leads

Condition: Blood Cell Counts

rs73036517 Condition: Blood Cell Counts Blood Cell Counts Condition rs73036517 rs73036517 MARK4

What the study found

Who was studied 170,384 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0508 lower (95% confidence interval 0.043-0.059); p = 5 × 10−35.

How common The G allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 19, band 19q13.32 — in an intron of EXOC3L2.

What each result means

A/A No copy of the version the research linked to Sum neutrophil eosinophil counts. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Sum neutrophil eosinophil counts. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Sum neutrophil eosinophil counts. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73036517

What is rs73036517?

rs73036517 is a single position in the genome, in or near the MARK4 gene. Published research associates it with sum neutrophil eosinophil counts. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73036517 linked to?

On MyGeneLog this position is linked to Blood Cell Counts. The research behind each link, and its sources, are set out on that condition page.

Does having rs73036517 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73036517 come from?

GWAS Catalog, Cell 2016, PMID:27863252. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Sum neutrophil eosinophil counts (rs73036517). MyGeneLog™. https://www.mygenelog.com/variants/rs73036517

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