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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 3,057 Black individuals, 10,769 European ancestry individuals.
The effect
Each copy of the T allele shifted the measure 0.14 higher (95% confidence interval 0.11-0.17); p = 2 × 10−24.
How common The T allele had a frequency of about 26% in the people studied.
Where it sits Chromosome 12, band 12q24.21 — between genes, 4.8 kb from LOC124903080.
What each result means
C/CNo copy of the version the research linked to Global electrical heterogeneity phenotypes. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Global electrical heterogeneity phenotypes. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Global electrical heterogeneity phenotypes. That is the strongest link of the three results. A link in a study is not a diagnosis.
Journal of the American Heart Association · 2018 · PMID 29622589 · open access
Questions about rs7301677
What is rs7301677?
rs7301677 is a single position in the genome, in or near the TBX3 gene. Published research associates it with global electrical heterogeneity phenotypes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs7301677 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7301677 come from?
GWAS Catalog, J Am Heart Assoc 2018, PMID:29622589. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Quoting this page
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Global electrical heterogeneity phenotypes (rs7301677). MyGeneLog™. https://www.mygenelog.com/variants/rs7301677