Standard

Asthma

MUC16 · rs73012738

Where this position leads

Condition: Asthma

rs73012738 Condition: Asthma Asthma Condition rs73012738 rs73012738 MUC16

What the study found

Who was studied 64,538 European ancestry cases, 239,321 European ancestry controls.

The effect The reported allele is G; the catalogue records no effect size ; p = 4 × 10−11.

How common The G allele had a frequency of about 32% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — between genes, 6.5 kb from BOLA3P2.

What each result means

G/G Two copies of the version the research linked to Asthma. That is the strongest link of the three results. A link in a study is not a diagnosis.
G/T One copy of the version the research linked to Asthma. That is a smaller link than two copies.
T/T No copy of the version the research linked to Asthma. This is the starting point the study compared everyone against.
Source

Questions about rs73012738

What is rs73012738?

rs73012738 is a single position in the genome, in or near the MUC16 gene. Published research associates it with asthma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73012738 linked to?

On MyGeneLog this position is linked to Asthma. The research behind each link, and its sources, are set out on that condition page.

Does having rs73012738 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73012738 come from?

GWAS Catalog, Nature communications 2020, PMID:32296059. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Asthma (rs73012738). MyGeneLog™. https://www.mygenelog.com/variants/rs73012738

← See all variants