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Total testosterone levels

near LARP4 · rs7300979

What the study found

Who was studied 148,248 British ancestry men.

The effect Each copy of the T allele shifted the measure 0.12 nmol/L lower (95% confidence interval 0.085-0.155); p = 2 × 10−11.

How common The T allele had a frequency of about 35% in the people studied.

Where it sits Chromosome 12, band 12q13.12 — between genes, 12.2 kb from LARP4.

What each result means

C/C No copy of the version the research linked to Total testosterone levels. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Total testosterone levels. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Total testosterone levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7300979

What is rs7300979?

rs7300979 is a single position in the genome, in or near the near LARP4 gene. Published research associates it with total testosterone levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7300979 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7300979 come from?

GWAS Catalog, Science advances 2021, PMID:34321204. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total testosterone levels (rs7300979). MyGeneLog™. https://www.mygenelog.com/variants/rs7300979

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