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Total cholesterol levels

ARMC6 · rs73008942

What the study found

Who was studied 342,508 European ancestry individuals, 6,014 African ancestry individuals, 7,336 South Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0956 lower (95% confidence interval 0.085-0.106); p = 3 × 10−67.

Where it sits Chromosome 19, band 19p13.11 — in an intron of ARMC6.

What each result means

A/A Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Total cholesterol levels compared to the general population.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Total cholesterol levels.
G/G Published research associates this genotype with typical/baseline likelihood of Total cholesterol levels — no copies of the reported risk allele.
Source

Questions about rs73008942

What is rs73008942?

rs73008942 is a single position in the genome, in or near the ARMC6 gene. Published research associates it with total cholesterol levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73008942 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73008942 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Total cholesterol levels (rs73008942). MyGeneLog™. https://www.mygenelog.com/variants/rs73008942

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