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PGLYRP2 protein levels

OR1I1 · rs73008835

What the study found

Who was studied 47,745 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.262 lower (95% confidence interval 0.2-0.33); p = 2 × 10−20.

How common The C allele had a frequency of about 1% in the people studied.

Where it sits Chromosome 19, band 19p13.12 — in the 3′ untranslated region of OR1I1.

What each result means

C/C Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of PGLYRP2 protein levels compared to the general population.
C/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with PGLYRP2 protein levels.
T/T Published research associates this genotype with typical/baseline likelihood of PGLYRP2 protein levels — no copies of the reported risk allele.
Source

Questions about rs73008835

What is rs73008835?

rs73008835 is a single position in the genome, in or near the OR1I1 gene. Published research associates it with pglyrp2 protein levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73008835 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73008835 come from?

GWAS Catalog, Nature genetics 2025, PMID:39789286. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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PGLYRP2 protein levels (rs73008835). MyGeneLog™. https://www.mygenelog.com/variants/rs73008835

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