Standard

ICD10 D25: Leiomyoma of uterus

NPAT · rs73006241

Where this position leads

Condition: Uterine Fibroids

rs73006241 Condition: Uterine Fibroids Uterine Fibroids Condition rs73006241 rs73006241 NPAT

What the study found

Who was studied 51,378 European ancestry cases, 243,913 European ancestry controls.

The effect Each copy of the T allele carried 1.11 times the odds of ICD10 D25: Leiomyoma of uterus (95% confidence interval 1.09-1.13); p = 1 × 10−25.

Where it sits Chromosome 11, band 11q22.3 — in an intron of NPAT.

What each result means

C/C No copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is a smaller link than two copies.
T/T Two copies of the version the research linked to ICD10 D25: Leiomyoma of uterus. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs73006241

What is rs73006241?

rs73006241 is a single position in the genome, in or near the NPAT gene. Published research associates it with icd10 d25: leiomyoma of uterus. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs73006241 linked to?

On MyGeneLog this position is linked to Uterine Fibroids. The research behind each link, and its sources, are set out on that condition page.

Does having rs73006241 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73006241 come from?

GWAS Catalog, Nature medicine 2025, PMID:40069456. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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ICD10 D25: Leiomyoma of uterus (rs73006241). MyGeneLog™. https://www.mygenelog.com/variants/rs73006241

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