Sensitive

Serum cancer antigen 125 (CA 125) levels

MUC16 · rs73005873

What the study found

Who was studied 9,824 Icelandic ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.14 higher (95% confidence interval 0.11-0.17); p = 2 × 10−17.

How common The A allele had a frequency of about 40% in the people studied.

Where it sits Chromosome 19, band 19p13.2 — in an intron of MUC16.

What each result means

A/A Two copies of the version the research linked to Serum cancer antigen 125 (CA 125) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Serum cancer antigen 125 (CA 125) levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to Serum cancer antigen 125 (CA 125) levels. This is the starting point the study compared everyone against.
Source

Questions about rs73005873

What is rs73005873?

rs73005873 is a single position in the genome, in or near the MUC16 gene. Published research associates it with serum cancer antigen 125 (ca 125) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73005873 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73005873 come from?

GWAS Catalog, Cancer epidemiology, biomarkers & prevention : a publication of the American Association for Cancer Research, cosponsored by the American Society of Preventive Oncology 2020, PMID:31666285. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

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Serum cancer antigen 125 (CA 125) levels (rs73005873). MyGeneLog™. https://www.mygenelog.com/variants/rs73005873

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