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rfMRI connectivity (ICA100 edge 659)

near ZIC4 · rs73004625

What the study found

Who was studied 21,081 British ancestry individuals; replicated in 10,607 British ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.077 higher (95% confidence interval 0.055-0.099); p = 5 × 10−12.

How common The C allele had a frequency of about 26% in the people studied.

Where it sits Chromosome 3, band 3q24 — between genes, 8.5 kb from ZIC4.

What each result means

C/C Two copies of the version the research linked to rfMRI connectivity (ICA100 edge 659). That is the strongest link of the three results. A link in a study is not a diagnosis.
C/T One copy of the version the research linked to rfMRI connectivity (ICA100 edge 659). That is a smaller link than two copies.
T/T No copy of the version the research linked to rfMRI connectivity (ICA100 edge 659). This is the starting point the study compared everyone against.
Source

Questions about rs73004625

What is rs73004625?

rs73004625 is a single position in the genome, in or near the near ZIC4 gene. Published research associates it with rfmri connectivity (ica100 edge 659). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs73004625 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs73004625 come from?

GWAS Catalog, Nature neuroscience 2021, PMID:33875891. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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rfMRI connectivity (ICA100 edge 659) (rs73004625). MyGeneLog™. https://www.mygenelog.com/variants/rs73004625

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