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Serum 25-Hydroxyvitamin D levels (conditioned on BMI)

DGAT2 · rs72997623

What the study found

Who was studied 417,580 European ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.029 higher (95% confidence interval 0.021-0.037); p = 6 × 10−16.

How common The C allele had a frequency of about 92% in the people studied.

Where it sits Chromosome 11, band 11q13.5 — in an intron of DGAT2.

What each result means

A/A No copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). This is the starting point the study compared everyone against.
A/C One copy of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is a smaller link than two copies.
C/C Two copies of the version the research linked to Serum 25-Hydroxyvitamin D levels (conditioned on BMI). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72997623

What is rs72997623?

rs72997623 is a single position in the genome, in or near the DGAT2 gene. Published research associates it with serum 25-hydroxyvitamin d levels (conditioned on bmi). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72997623 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72997623 come from?

GWAS Catalog, Nature communications 2020, PMID:32242144. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Serum 25-Hydroxyvitamin D levels (conditioned on BMI) (rs72997623). MyGeneLog™. https://www.mygenelog.com/variants/rs72997623

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