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Who was studied 29,640 European ancestry female cases, 736,610 European ancestry female controls, 3,921 South Asian ancestry female cases, 14,233 South Asian ancestry female controls, 4,346 East Asian ancestry female cases, 23,286 East Asian ancestry female controls, 244 Hispanic or Latin American female cases, 744 Hispanic or Latin American female controls, 154 African American or Afro-Caribbean female cases, 1,272 African American or Afro-Caribbean female controls.
The effect
The reported allele is A; the catalogue records no effect size
; p = 2 × 10−22.
How common The A allele had a frequency of about 79% in the people studied.
Where it sits Chromosome 3, band 3q21.1 — in an intron of ADCY5.
What each result means
A/ATwo copies of the version the research linked to Gestational diabetes. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/COne copy of the version the research linked to Gestational diabetes. That is a smaller link than two copies.
C/CNo copy of the version the research linked to Gestational diabetes. This is the starting point the study compared everyone against.
Nature communications · 2026 · PMID 42225636 · open access
Questions about rs72964564
What is rs72964564?
rs72964564 is a single position in the genome, in or near the ADCY5 gene. Published research associates it with gestational diabetes. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72964564 linked to?
On MyGeneLog this position is linked to Gestational Diabetes Mellitus. The research behind each link, and its sources, are set out on that condition page.
Does having rs72964564 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72964564 come from?
GWAS Catalog, Nature communications 2026, PMID:42225636. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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