Who was studied 20,917 European ancestry cases, 440,906 European ancestry controls, 14,992 East Asian ancestry cases, 146,214 East Asian ancestry controls.
The effect
Each copy of the G allele shifted the measure 0.103 higher (95% confidence interval 0.082-0.124); p = 3 × 10−21.
Where it sits Chromosome 4, band 4q31.22 — between genes, 2.1 kb from EDNRA.
What each result means
A/APublished research associates this genotype with typical/baseline likelihood of Myocardial infarction — no copies of the reported risk allele.
A/GPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Myocardial infarction.
G/GPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Myocardial infarction compared to the general population.
rs72957606 is a single position in the genome, in or near the near EDNRA gene. Published research associates it with myocardial infarction. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72957606 linked to?
On MyGeneLog this position is linked to Myocardial Infarction. The research behind each link, and its sources, are set out on that condition page.
Does having rs72957606 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72957606 come from?
GWAS Catalog, Nature genetics 2021, PMID:34594039. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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