Sensitive

Finger osteoarthritis

C12orf60 · rs7294636

Where this position leads

Condition: Osteoarthritis

rs7294636 Condition: Osteoarthritis Osteoarthritis Condition rs7294636 rs7294636 C12orf60

What the study found

Who was studied 10,804 European ancestry cases, 255,814 European ancestry controls.

The effect Each copy of the A allele carried 1.16 times the odds of Finger osteoarthritis (95% confidence interval 1.118200445-1.199949355); p = 3 × 10−16.

How common The A allele had a frequency of about 37% in the people studied.

Where it sits Chromosome 12, band 12p12.3 — inside C12orf60.

What each result means

A/A Two copies of the version the research linked to Finger osteoarthritis. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Finger osteoarthritis. That is a smaller link than two copies.
G/G No copy of the version the research linked to Finger osteoarthritis. This is the starting point the study compared everyone against.
Source

Questions about rs7294636

What is rs7294636?

rs7294636 is a single position in the genome, in or near the C12orf60 gene. Published research associates it with finger osteoarthritis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs7294636 linked to?

On MyGeneLog this position is linked to Osteoarthritis. The research behind each link, and its sources, are set out on that condition page.

Does having rs7294636 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7294636 come from?

GWAS Catalog, Cell 2021, PMID:34450027. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Finger osteoarthritis (rs7294636). MyGeneLog™. https://www.mygenelog.com/variants/rs7294636

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