Estimated glomerular filtration rate in non-diabetics
MTX2 · rs72938846
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Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 152,624 European ancestry individuals, 36,369 African American individuals.
The effect
Each copy of the T allele shifted the measure 1.23 higher (95% confidence interval 0.86-1.6); p = 7 × 10−11.
How common The T allele had a frequency of about 97% in the people studied.
Where it sits Chromosome 2, band 2q31.1 — between genes, 15.3 kb from PPIAP67.
What each result means
C/CNo copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Estimated glomerular filtration rate in non-diabetics. That is the strongest link of the three results. A link in a study is not a diagnosis.
Nature communications · 2019 · PMID 31451708 · open access
Questions about rs72938846
What is rs72938846?
rs72938846 is a single position in the genome, in or near the MTX2 gene. Published research associates it with estimated glomerular filtration rate in non-diabetics. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs72938846 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72938846 come from?
GWAS Catalog, Nature communications 2019, PMID:31451708. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
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Estimated glomerular filtration rate in non-diabetics (rs72938846). MyGeneLog™. https://www.mygenelog.com/variants/rs72938846