Standard
Corneal endothelial cell shape (percentage of hexagonally shaped cells)
near TCF4 · rs72932578
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
C/C
Published research associates this genotype with typical/baseline likelihood of Corneal endothelial cell shape (percentage of hexagonally shaped cells) — no copies of the reported risk allele.
C/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Corneal endothelial cell shape (percentage of hexagonally shaped cells).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Corneal endothelial cell shape (percentage of hexagonally shaped cells) compared to the general population.
Source
Sequence variation at ANAPC1 accounts for 24% of the variability in corneal endothelial cell density
Ivarsdottir EV,
Benonisdottir S,
Thorleifsson G,
Sulem P,
Oddsson A,
Styrkarsdottir U,
Kristmundsdottir S,
Arnadottir GA,
Thorgeirsson G,
Jonsdottir I,
Zoega GM,
Thorsteinsdottir U
and 4 more — show all
Nature communications · 2019 · PMID 30894546 · open access
Questions about rs72932578
What is rs72932578?
rs72932578 is a single position in the genome, in or near the near TCF4 gene. Published research associates it with corneal endothelial cell shape (percentage of hexagonally shaped cells). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs72932578 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72932578 come from?
GWAS Catalog, Nat Commun 2019, PMID:30894546. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants