Standard

Blond vs. brown/black hair color

near TPCN2 · rs72932523

Where this position leads

Condition: Hair Color

rs72932523 Condition: Hair Color Hair Color Condition rs72932523 rs72932523 near TPCN2

What the study found

Who was studied 12,398 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.446 lower (95% confidence interval 0.31-0.58); p = 2 × 10−10.

Where it sits Chromosome 11, band 11q13.3 — between genes, 2.3 kb from TPCN2.

What each result means

A/A Published research associates this genotype with typical/baseline likelihood of Blond vs. brown/black hair color — no copies of the reported risk allele.
A/G Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Blond vs. brown/black hair color.
G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Blond vs. brown/black hair color compared to the general population.
Source

Questions about rs72932523

What is rs72932523?

rs72932523 is a single position in the genome, in or near the near TPCN2 gene. Published research associates it with blond vs. brown/black hair color. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72932523 linked to?

On MyGeneLog this position is linked to Hair Color. The research behind each link, and its sources, are set out on that condition page.

Does having rs72932523 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72932523 come from?

GWAS Catalog, Communications biology 2021, PMID:34737440. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Blond vs. brown/black hair color (rs72932523). MyGeneLog™. https://www.mygenelog.com/variants/rs72932523

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