Paradoxical eczema in biologic-treated plaque psoriasis
SLC1A2 · rs72925168
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Who was studied 88 European ancestry cases, 3,124 European ancestry controls.
The effect
Each copy of the G allele carried 4.98 times the odds of Paradoxical eczema in biologic-treated plaque psoriasis (95% confidence interval 2.96-8.4); p = 2 × 10−9.
How common The G allele had a frequency of about 3% in the people studied.
Where it sits Chromosome 11, band 11p13 — in an intron of SLC1A2.
What each result means
A/ANo copy of the version the research linked to Paradoxical eczema in biologic-treated plaque psoriasis. This is the starting point the study compared everyone against.
A/GOne copy of the version the research linked to Paradoxical eczema in biologic-treated plaque psoriasis. That is a smaller link than two copies.
G/GTwo copies of the version the research linked to Paradoxical eczema in biologic-treated plaque psoriasis. That is the strongest link of the three results. A link in a study is not a diagnosis.
The Journal of investigative dermatology · 2023 · PMID 36804406
Questions about rs72925168
What is rs72925168?
rs72925168 is a single position in the genome, in or near the SLC1A2 gene. Published research associates it with paradoxical eczema in biologic-treated plaque psoriasis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72925168 linked to?
On MyGeneLog this position is linked to Psoriasis. The research behind each link, and its sources, are set out on that condition page.
Does having rs72925168 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72925168 come from?
GWAS Catalog, The Journal of investigative dermatology 2023, PMID:36804406. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 33Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others3Total3Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Paradoxical eczema in biologic-treated plaque psoriasis (rs72925168). MyGeneLog™. https://www.mygenelog.com/variants/rs72925168