G/GPublished research associates this genotype with typical/baseline likelihood of Dupuytren's disease — no copies of the reported risk allele.
G/TPublished research associates this genotype (one copy of the reported risk allele) with an intermediate association with Dupuytren's disease.
T/TPublished research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Dupuytren's disease compared to the general population.
American journal of human genetics · 2017 · PMID 28886342 · open access
Questions about rs7291412
What is rs7291412?
rs7291412 is a single position in the genome, in or near the WNT7B gene. Published research associates it with dupuytren's disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs7291412 linked to?
On MyGeneLog this position is linked to Dupuytren's Disease. The research behind each link, and its sources, are set out on that condition page.
Does having rs7291412 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs7291412 come from?
GWAS Catalog, Am J Hum Genet 2017, PMID:28886342. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.