near TCF4 · rs729053
Stands on its own. Nothing else here links to this position yet — but the page above is the point: what the research found, what each genotype means, and where it came from, in language you can read. Links to conditions, drugs and the senses appear automatically if we write them.
What the study found
Who was studied 85,613 European ancestry cases, 164,172 European ancestry controls, 15,714 African American or Afro-Caribbean cases, 19,756 African American or Afro-Caribbean controls, 10,167 Hispanic or Latin American cases, 9,063 Hispanic or Latin American controls.
The effect Each copy of the C allele shifted the measure 0.04 z score higher; p = 1 × 10−11.
How common The C allele had a frequency of about 32% in the people studied.
Where it sits Chromosome 18, band 18q21.2 — between genes, 4.1 kb from RNA5SP459.
rs729053 is a single position in the genome, in or near the near TCF4 gene. Published research associates it with traumatic brain injury (tbi). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
GWAS Catalog, Molecular psychiatry 2024, PMID:37875548. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.
Traumatic brain injury (TBI) (rs729053). MyGeneLog™. https://www.mygenelog.com/variants/rs729053