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Smoking initiation

MIRLET7BHG · rs7289813

What the study found

Who was studied 3,382,012 European ancestry, East Asian ancestry, Hispanic or Latin American, African ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.00623 lower (95% confidence interval 0.0047-0.0078); p = 6 × 10−16.

How common The G allele had a frequency of about 41% in the people studied.

Where it sits Chromosome 22, band 22q13.31 — in an intron of MIRLET7BHG.

What each result means

A/A No copy of the version the research linked to Smoking initiation. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Smoking initiation. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Smoking initiation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs7289813

What is rs7289813?

rs7289813 is a single position in the genome, in or near the MIRLET7BHG gene. Published research associates it with smoking initiation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs7289813 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs7289813 come from?

GWAS Catalog, Nature 2022, PMID:36477530. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Smoking initiation (rs7289813). MyGeneLog™. https://www.mygenelog.com/variants/rs7289813

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