Standard

Waist circumference adjusted for body mass index

RP11-739L10.1 · rs72885774

Where this position leads

Condition: Waist Circumference

rs72885774 Condition: Waist Circumference Waist Circumference Condition rs72885774 rs72885774 RP11-739L10.1

What the study found

Who was studied 186,825 British ancestry men.

The effect Each copy of the G allele shifted the measure 0.0284 lower (95% confidence interval 0.02-0.037); p = 2 × 10−10.

Where it sits Chromosome 18, band 18q11.2 — in an intron of RBBP8.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Waist circumference adjusted for body mass index compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Waist circumference adjusted for body mass index.
T/T Published research associates this genotype with typical/baseline likelihood of Waist circumference adjusted for body mass index — no copies of the reported risk allele.
Source

Questions about rs72885774

What is rs72885774?

rs72885774 is a single position in the genome, in or near the RP11-739L10.1 gene. Published research associates it with waist circumference adjusted for body mass index. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72885774 linked to?

On MyGeneLog this position is linked to Waist Circumference. The research behind each link, and its sources, are set out on that condition page.

Does having rs72885774 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72885774 come from?

GWAS Catalog, Scientific reports 2021, PMID:34021172. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Waist circumference adjusted for body mass index (rs72885774). MyGeneLog™. https://www.mygenelog.com/variants/rs72885774

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