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Who was studied at least 757,601 European ancestry individuals (MTAG boosted by 455,258 Alzheimer's disease samples).
The effect
Each copy of the A allele shifted the measure 0.025 higher (95% confidence interval 0.017-0.033); p = 1 × 10−10.
Where it sits Chromosome 10, band 10q24.31 — between genes, 23.7 kb from Y_RNA.
What each result means
A/ATwo copies of the version the research linked to Diastolic blood pressure (MTAG). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/GOne copy of the version the research linked to Diastolic blood pressure (MTAG). That is a smaller link than two copies.
G/GNo copy of the version the research linked to Diastolic blood pressure (MTAG). This is the starting point the study compared everyone against.
Nature communications · 2024 · PMID 39537608 · open access
Questions about rs72846661
What is rs72846661?
rs72846661 is a single position in the genome, in or near the near Y_RNA gene. Published research associates it with diastolic blood pressure (mtag). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72846661 linked to?
On MyGeneLog this position is linked to Blood Pressure. The research behind each link, and its sources, are set out on that condition page.
Does having rs72846661 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72846661 come from?
GWAS Catalog, Nature communications 2024, PMID:39537608. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 422Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon2Apple0China (ByteDance, Huawei, Baidu…)0Others2Total4Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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