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Triglycerides to total lipids in large VLDL percentage (UKB data field 23593)

HLA-DQB1 · rs72844401

What the study found

Who was studied 88,321 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.0518 lower (95% confidence interval 0.039-0.065); p = 5 × 10−15.

How common The A allele had a frequency of about 15% in the people studied.

Where it sits Chromosome 6, band 6p21.32 — inside HLA-DQB1.

What each result means

A/A Two copies of the version the research linked to Triglycerides to total lipids in large VLDL percentage (UKB data field 23593). That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Triglycerides to total lipids in large VLDL percentage (UKB data field 23593). That is a smaller link than two copies.
G/G No copy of the version the research linked to Triglycerides to total lipids in large VLDL percentage (UKB data field 23593). This is the starting point the study compared everyone against.
Source

Questions about rs72844401

What is rs72844401?

rs72844401 is a single position in the genome, in or near the HLA-DQB1 gene. Published research associates it with triglycerides to total lipids in large vldl percentage (ukb data field 23593). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72844401 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72844401 come from?

GWAS Catalog, Biological psychiatry 2023, PMID:36764567. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglycerides to total lipids in large VLDL percentage (UKB data field 23593) (rs72844401). MyGeneLog™. https://www.mygenelog.com/variants/rs72844401

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