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Hip bone size

TBX4 · rs72834687

What the study found

Who was studied 28,900 European ancestry individuals; replicated in 7,912 European ancestry individuals, 5,699 East Asian ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.048 lower (95% confidence interval 0.032-0.064); p = 3 × 10−9.

How common The A allele had a frequency of about 24% in the people studied.

Where it sits Chromosome 17, band 17q23.2 — in an intron of TBX4.

What each result means

A/A Two copies of the version the research linked to Hip bone size. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Hip bone size. That is a smaller link than two copies.
G/G No copy of the version the research linked to Hip bone size. This is the starting point the study compared everyone against.
Source

Questions about rs72834687

What is rs72834687?

rs72834687 is a single position in the genome, in or near the TBX4 gene. Published research associates it with hip bone size. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72834687 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72834687 come from?

GWAS Catalog, Nat Commun 2019, PMID:31053729. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Hip bone size (rs72834687). MyGeneLog™. https://www.mygenelog.com/variants/rs72834687

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