Decreased low contrast letter acuity in multiple sclerosis
MSI2 · rs72830848
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 582 European and unknown ancestry individuals; replicated in 253 European and unknown ancestry individuals.
The effect
Each copy of the T allele carried 2.25 times the odds of Decreased low contrast letter acuity in multiple sclerosis (95% confidence interval 1.78-2.85); p = 4 × 10−8.
How common The T allele had a frequency of about 6% in the people studied.
Where it sits Chromosome 17, band 17q22 — in an intron of MSI2.
What each result means
C/CNo copy of the version the research linked to Decreased low contrast letter acuity in multiple sclerosis. This is the starting point the study compared everyone against.
C/TOne copy of the version the research linked to Decreased low contrast letter acuity in multiple sclerosis. That is a smaller link than two copies.
T/TTwo copies of the version the research linked to Decreased low contrast letter acuity in multiple sclerosis. That is the strongest link of the three results. A link in a study is not a diagnosis.
Brain : a journal of neurology · 2019 · PMID 31289819
Questions about rs72830848
What is rs72830848?
rs72830848 is a single position in the genome, in or near the MSI2 gene. Published research associates it with decreased low contrast letter acuity in multiple sclerosis. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72830848 linked to?
On MyGeneLog this position is linked to Multiple Sclerosis. The research behind each link, and its sources, are set out on that condition page.
Does having rs72830848 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72830848 come from?
GWAS Catalog, Brain : a journal of neurology 2019, PMID:31289819. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 22Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity0Meta AI0Microsoft · Copilot0Amazon0Apple0China (ByteDance, Huawei, Baidu…)0Others2Total2Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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Decreased low contrast letter acuity in multiple sclerosis (rs72830848). MyGeneLog™. https://www.mygenelog.com/variants/rs72830848