Standard

Estimated glomerular filtration rate (cystatin c)

near TRIM64FP · rs72821435

What the study found

Who was studied 406,504 European ancestry individuals.

The effect Each copy of the T allele shifted the measure 0.013 higher; p = 9 × 10−10.

Where it sits Chromosome 2, band 2q11.1 — between genes, 2.1 kb from TRIM64FP.

What each result means

C/C No copy of the version the research linked to Estimated glomerular filtration rate (cystatin c). This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Estimated glomerular filtration rate (cystatin c). That is a smaller link than two copies.
T/T Two copies of the version the research linked to Estimated glomerular filtration rate (cystatin c). That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72821435

What is rs72821435?

rs72821435 is a single position in the genome, in or near the near TRIM64FP gene. Published research associates it with estimated glomerular filtration rate (cystatin c). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72821435 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72821435 come from?

GWAS Catalog, Nature genetics 2024, PMID:39256582. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Estimated glomerular filtration rate (cystatin c) (rs72821435). MyGeneLog™. https://www.mygenelog.com/variants/rs72821435

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