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Anxiety

WDPCP · rs72813408

Where this position leads

Condition: Anxiety Disorder

rs72813408 Condition: Anxiety Disorder Anxiety Disorder Condition rs72813408 rs72813408 WDPCP

What the study found

Who was studied at least 23,606 European ancestry cases, at least 113,351 European ancestry controls; replicated in 624,615 European ancestry cases, 1,310,854 European ancestry controls.

The effect Each copy of the G allele shifted the measure 0.024 higher (95% confidence interval 0.017-0.031); p = 3 × 10−16.

How common The G allele had a frequency of about 19% in the people studied.

Where it sits Chromosome 2, band 2p15 — in an intron of WDPCP.

What each result means

G/G Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Anxiety compared to the general population.
G/T Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Anxiety.
T/T Published research associates this genotype with typical/baseline likelihood of Anxiety — no copies of the reported risk allele.
Source

Questions about rs72813408

What is rs72813408?

rs72813408 is a single position in the genome, in or near the WDPCP gene. Published research associates it with anxiety. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72813408 linked to?

On MyGeneLog this position is linked to Anxiety Disorder. The research behind each link, and its sources, are set out on that condition page.

Does having rs72813408 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72813408 come from?

GWAS Catalog, Nature human behaviour 2021, PMID:33859377. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Anxiety (rs72813408). MyGeneLog™. https://www.mygenelog.com/variants/rs72813408

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