Standard

Heart failure

near ARHGAP26 · rs72801029

Where this position leads

Condition: Heart Failure

rs72801029 Condition: Heart Failure Heart Failure Condition rs72801029 rs72801029 near ARHGAP26

What the study found

Who was studied 168,363 European ancestry cases, 1,725,558 European ancestry controls, 21,202 African ancestry cases, 121,670 African ancestry controls, 12,665 East Asian ancestry cases, 245,263 East Asian ancestry controls, 5,116 Hispanic or Latin American cases, 58,719 Hispanic or Latin American controls.

The effect Each copy of the T allele shifted the measure 0.0369 lower (95% confidence interval 0.027-0.047); p = 4 × 10−13.

How common The T allele had a frequency of about 84% in the people studied.

Where it sits Chromosome 5, band 5q31.3 — between genes, 17.2 kb from ARHGAP26.

What each result means

C/C No copy of the version the research linked to Heart failure. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Heart failure. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Heart failure. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72801029

What is rs72801029?

rs72801029 is a single position in the genome, in or near the near ARHGAP26 gene. Published research associates it with heart failure. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72801029 linked to?

On MyGeneLog this position is linked to Heart Failure. The research behind each link, and its sources, are set out on that condition page.

Does having rs72801029 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72801029 come from?

GWAS Catalog, Nature genetics 2025, PMID:40195560. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Heart failure (rs72801029). MyGeneLog™. https://www.mygenelog.com/variants/rs72801029

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