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Atrial fibrillation

SLC27A6 · rs72797161

Where this position leads

Condition: Atrial Fibrillation

rs72797161 Condition: Atrial Fibrillation Atrial Fibrillation Condition rs72797161 rs72797161 SLC27A6

What the study found

Who was studied 252,438 European ancestry cases, 1,959,739 European ancestry controls, 9,826 East Asian ancestry cases, 140,446 East Asian ancestry controls, 754 South Asian ancestry cases, 52,054 South Asian ancestry controls, 9,485 African ancestry cases, 109,006 African ancestry controls, 3,447 Admixed American ancestry cases, 46,818 Admixed American ancestry controls.

The effect Each copy of the T allele shifted the measure 0.0499 lower (95% confidence interval 0.042-0.058); p = 2 × 10−33.

How common The T allele had a frequency of about 21% in the people studied.

Where it sits Chromosome 5, band 5q23.3 — inside SLC27A6.

What each result means

C/C No copy of the version the research linked to Atrial fibrillation. This is the starting point the study compared everyone against.
C/T One copy of the version the research linked to Atrial fibrillation. That is a smaller link than two copies.
T/T Two copies of the version the research linked to Atrial fibrillation. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72797161

What is rs72797161?

rs72797161 is a single position in the genome, in or near the SLC27A6 gene. Published research associates it with atrial fibrillation. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72797161 linked to?

On MyGeneLog this position is linked to Atrial Fibrillation. The research behind each link, and its sources, are set out on that condition page.

Does having rs72797161 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72797161 come from?

GWAS Catalog, Nature communications 2025, PMID:40645996. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Atrial fibrillation (rs72797161). MyGeneLog™. https://www.mygenelog.com/variants/rs72797161

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