Sensitive

Graves' disease

CTNNA3 · rs72791568

Where this position leads

Condition: Graves' Disease

rs72791568 Condition: Graves' Disease Graves' Disease Condition rs72791568 rs72791568 CTNNA3

What the study found

Who was studied 2,270 African ancestry cases, 207,823 African ancestry controls.

The effect Each copy of the A allele shifted the measure 1.66 higher (95% confidence interval 1.14-2.18); p = 4 × 10−10.

How common The A allele had a frequency of about 0% in the people studied.

Where it sits Chromosome 10, band 10q21.3 — in an intron of CTNNA3.

What each result means

A/A Two copies of the version the research linked to Graves' disease. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Graves' disease. That is a smaller link than two copies.
G/G No copy of the version the research linked to Graves' disease. This is the starting point the study compared everyone against.
Source

Questions about rs72791568

What is rs72791568?

rs72791568 is a single position in the genome, in or near the CTNNA3 gene. Published research associates it with graves' disease. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72791568 linked to?

On MyGeneLog this position is linked to Graves' Disease. The research behind each link, and its sources, are set out on that condition page.

Does having rs72791568 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72791568 come from?

GWAS Catalog, Nature genetics 2026, PMID:41644669. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Graves' disease (rs72791568). MyGeneLog™. https://www.mygenelog.com/variants/rs72791568

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