Standard
Multiple myeloma (survival)
MYH11 · rs72773978
Stands on its own.
Nothing else here links to this position yet — but the page above is the point: what the
research found, what each genotype means, and where it came from, in language you can
read. Links to conditions, drugs and the senses appear automatically if we write them.
What each result means
A/A
Published research associates this genotype with typical/baseline likelihood of Multiple myeloma (survival) — no copies of the reported risk allele.
A/T
Published research associates this genotype (one copy of the reported risk allele) with an intermediate association with Multiple myeloma (survival).
T/T
Published research associates this genotype (two copies of the reported risk allele) with a higher likelihood of Multiple myeloma (survival) compared to the general population.
Source
Genome-wide association study identifies variants at 16p13 associated with survival in multiple myeloma patients
Ziv E,
Dean E,
Hu D,
Martino A,
Serie D,
Curtin K,
Campa D,
Aftab B,
Bracci P,
Buda G,
Zhao Y,
Caswell-Jin J
and 27 more — show all
Diasio R,
Dumontet C,
Dudziński M,
Fejerman L,
Greenberg A,
Huntsman S,
Jamroziak K,
Jurczyszyn A,
Kumar S,
Atanackovic D,
Glenn M,
Cannon-Albright LA,
Jones B,
Lee A,
Marques H,
Martin T,
Martinez-Lopez J,
Martinez-Lopez J,
Rajkumar V,
Sainz J,
Vangsted AJ,
Wątek M,
Wolf J,
Slager S,
Camp NJ,
Canzian F,
Vachon C
Nature communications · 2015 · PMID 26198393
Questions about rs72773978
What is rs72773978?
rs72773978 is a single position in the genome, in or near the MYH11 gene. Published research associates it with multiple myeloma (survival). A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
Does having rs72773978 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72773978 come from?
GWAS Catalog, Nat Commun 2015, PMID:26198393. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
← See all variants