Sensitive

Barrett's esophagus or Esophageal adenocarcinoma

near NNT · rs72760500

Where this position leads

Condition: Oesophageal Cancer

rs72760500 Condition: Oesophageal Cancer Oesophageal Cancer Condition rs72760500 rs72760500 near NNT

What the study found

Who was studied 16,790 European ancestry cases, 32,476 European ancestry controls.

The effect Each copy of the A allele shifted the measure 0.227 higher (95% confidence interval 0.17-0.29); p = 2 × 10−13.

How common The A allele had a frequency of about 6% in the people studied.

Where it sits Chromosome 5, band 5p12 — between genes, 78.2 kb from NNT.

What each result means

A/A Two copies of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. That is a smaller link than two copies.
G/G No copy of the version the research linked to Barrett's esophagus or Esophageal adenocarcinoma. This is the starting point the study compared everyone against.
Source

Questions about rs72760500

What is rs72760500?

rs72760500 is a single position in the genome, in or near the near NNT gene. Published research associates it with barrett's esophagus or esophageal adenocarcinoma. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72760500 linked to?

On MyGeneLog this position is linked to Oesophageal Cancer. The research behind each link, and its sources, are set out on that condition page.

Does having rs72760500 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72760500 come from?

GWAS Catalog, Gut 2023, PMID:35882562. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

Free to quote and reuse under CC BY 4.0. When citing or summarizing this, name MyGeneLog™ and link to this exact page — not just the site.

Barrett's esophagus or Esophageal adenocarcinoma (rs72760500). MyGeneLog™. https://www.mygenelog.com/variants/rs72760500

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