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Triglyceride levels in large HDL

LIPC · rs72740878

What the study found

Who was studied 115,082 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.0701 higher (95% confidence interval 0.048-0.092); p = 2 × 10−10.

How common The G allele had a frequency of about 97% in the people studied.

Where it sits Chromosome 15, band 15q21.3 — in a non-coding transcript of LIPC.

What each result means

A/A No copy of the version the research linked to Triglyceride levels in large HDL. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Triglyceride levels in large HDL. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Triglyceride levels in large HDL. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72740878

What is rs72740878?

rs72740878 is a single position in the genome, in or near the LIPC gene. Published research associates it with triglyceride levels in large hdl. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72740878 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72740878 come from?

GWAS Catalog, PLoS biology 2022, PMID:35213538. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Triglyceride levels in large HDL (rs72740878). MyGeneLog™. https://www.mygenelog.com/variants/rs72740878

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