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Urinary 3-aminoisobutyrate to urinary creatinine ratio

TTC23L · rs72732827

What the study found

Who was studied 6,347 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.62 lower (95% confidence interval 0.46-0.78); p = 6 × 10−14.

How common The A allele had a frequency of about 99% in the people studied.

Where it sits Chromosome 5, band 5p13.2 — in an intron of TTC23L.

What each result means

A/A Two copies of the version the research linked to Urinary 3-aminoisobutyrate to urinary creatinine ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/T One copy of the version the research linked to Urinary 3-aminoisobutyrate to urinary creatinine ratio. That is a smaller link than two copies.
T/T No copy of the version the research linked to Urinary 3-aminoisobutyrate to urinary creatinine ratio. This is the starting point the study compared everyone against.
Source

Questions about rs72732827

What is rs72732827?

rs72732827 is a single position in the genome, in or near the TTC23L gene. Published research associates it with urinary 3-aminoisobutyrate to urinary creatinine ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72732827 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72732827 come from?

GWAS Catalog, Nature communications 2025, PMID:39746953. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Urinary 3-aminoisobutyrate to urinary creatinine ratio (rs72732827). MyGeneLog™. https://www.mygenelog.com/variants/rs72732827

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