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X-17676 levels

BPHL · rs727260

What the study found

Who was studied 8,118 European ancestry individuals.

The effect Each copy of the A allele shifted the measure 0.301 lower (95% confidence interval 0.23-0.37); p = 4 × 10−17.

How common The A allele had a frequency of about 5% in the people studied.

Where it sits Chromosome 6, band 6p25.2 — in an intron of BPHL.

What each result means

A/A Two copies of the version the research linked to X-17676 levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
A/G One copy of the version the research linked to X-17676 levels. That is a smaller link than two copies.
G/G No copy of the version the research linked to X-17676 levels. This is the starting point the study compared everyone against.
Source

Questions about rs727260

What is rs727260?

rs727260 is a single position in the genome, in or near the BPHL gene. Published research associates it with x-17676 levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs727260 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs727260 come from?

GWAS Catalog, Nature genetics 2023, PMID:36635386. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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X-17676 levels (rs727260). MyGeneLog™. https://www.mygenelog.com/variants/rs727260

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