0 19132346Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others6Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
Who was studied 48,843 European ancestry cases, 1,190,837 European ancestry controls.
The effect
The reported allele is C; the catalogue records no effect size
; p = 4 × 10−12.
How common The C allele had a frequency of about 4% in the people studied.
Where it sits Chromosome 14, band 14q24.3 — inside TTLL5.
What ClinVar records
ClassificationBenign; criteria provided, multiple submitters, no conflicts (2 of 4 stars, 3 submitters), last evaluated 2026-02-02.
ClinVar record 1170254NM_015072.5(TTLL5):c.2388-12T>C
What this is ClinVar's aggregate record for this position (as of its 2026-10-12 release), not a result about you. A classification describes the variant against the condition named, as laboratories submitted it. Whether a person carries this variant, and what that would mean for them, is a question for a clinical test and a genetic counsellor.
What each result means
C/CTwo copies of the version the research linked to Carpal tunnel syndrome. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/TOne copy of the version the research linked to Carpal tunnel syndrome. That is a smaller link than two copies.
T/TNo copy of the version the research linked to Carpal tunnel syndrome. This is the starting point the study compared everyone against.
Nature communications · 2022 · PMID 35332129 · open access
Questions about rs72725608
What is rs72725608?
rs72725608 is a single position in the genome, in or near the TTLL5 gene. Published research associates it with carpal tunnel syndrome. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.
What conditions is rs72725608 linked to?
On MyGeneLog this position is linked to Carpal Tunnel Syndrome. The research behind each link, and its sources, are set out on that condition page.
Does having rs72725608 mean I will get this?
No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.
Where does the information about rs72725608 come from?
GWAS Catalog, Nature communications 2022, PMID:35332129. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.
0 19132346Reads by AI crawlersClaude0ChatGPT0Google · Gemini0Perplexity1Meta AI3Microsoft · Copilot0Amazon2Apple3China (ByteDance, Huawei, Baidu…)4ByteDance (Doubao)4Others6Total19Counted by the name each crawler declares; requests found to be impersonating one are left out. Google · Gemini includes Googlebot, the search crawler whose index Google also uses for its AI features. Other search engines and bots are under Others.
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