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Alkenylphosphatidylcholine (P-16:0/16:0) levels

TMEM229B · rs72721018

What the study found

Who was studied 4,492 European ancestry individuals.

The effect Each copy of the G allele shifted the measure 0.27 higher (95% confidence interval 0.22-0.32); p = 4 × 10−21.

Where it sits Chromosome 14, band 14q24.1 — in a regulatory region of TMEM229B.

What each result means

A/A No copy of the version the research linked to Alkenylphosphatidylcholine (P-16:0/16:0) levels. This is the starting point the study compared everyone against.
A/G One copy of the version the research linked to Alkenylphosphatidylcholine (P-16:0/16:0) levels. That is a smaller link than two copies.
G/G Two copies of the version the research linked to Alkenylphosphatidylcholine (P-16:0/16:0) levels. That is the strongest link of the three results. A link in a study is not a diagnosis.
Source

Questions about rs72721018

What is rs72721018?

rs72721018 is a single position in the genome, in or near the TMEM229B gene. Published research associates it with alkenylphosphatidylcholine (p-16:0/16:0) levels. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

Does having rs72721018 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72721018 come from?

GWAS Catalog, Nature communications 2022, PMID:35668104. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Alkenylphosphatidylcholine (P-16:0/16:0) levels (rs72721018). MyGeneLog™. https://www.mygenelog.com/variants/rs72721018

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