Standard

Aspartate aminotransferase to alanine aminotransferase ratio

ARHGAP39 · rs72697668

Where this position leads

Condition: Gout

rs72697668 Condition: Gout Gout Condition rs72697668 rs72697668 ARHGAP39

What the study found

Who was studied 341,165 European ancestry individuals, 5,981 African ancestry individuals, 7,309 South Asian ancestry individuals.

The effect Each copy of the C allele shifted the measure 0.0291 lower (95% confidence interval 0.019-0.039); p = 4 × 10−9.

Where it sits Chromosome 8, band 8q24.3 — in an intron of ARHGAP39.

What each result means

C/C Two copies of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is the strongest link of the three results. A link in a study is not a diagnosis.
C/G One copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. That is a smaller link than two copies.
G/G No copy of the version the research linked to Aspartate aminotransferase to alanine aminotransferase ratio. This is the starting point the study compared everyone against.
Source

Questions about rs72697668

What is rs72697668?

rs72697668 is a single position in the genome, in or near the ARHGAP39 gene. Published research associates it with aspartate aminotransferase to alanine aminotransferase ratio. A single variant does not decide an outcome — it shifts a probability, and for most common variants the shift is small.

What conditions is rs72697668 linked to?

On MyGeneLog this position is linked to Gout. The research behind each link, and its sources, are set out on that condition page.

Does having rs72697668 mean I will get this?

No. Common variants like this one move a probability slightly and, on their own, rarely decide anything about one person. Nothing on this page is a diagnosis, and health decisions should be made with a clinician who can see your whole picture.

Where does the information about rs72697668 come from?

GWAS Catalog, Nature genetics 2021, PMID:33462484. Every variant on MyGeneLog comes from public primary sources and is published with its citation and the date it was checked.

Quoting this page

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Aspartate aminotransferase to alanine aminotransferase ratio (rs72697668). MyGeneLog™. https://www.mygenelog.com/variants/rs72697668

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